Frontotemporal Dementia and Alzheimer's Disease



Similarities and Differences (from What if it's not Alzheimer's - A caregiver's guide to dementia - Lisa Radin and Gary Radin)

Features
FTD
AD
Age at which disease generally occurs
  • Common between 40 and 70 years
  • common in the elderly
Brain areas affected
  • Frontal and Temporal lobes
  • Starts in the medial temporal area, usually in the hippocampus
  • spreads to the other areas of the brain
Pathologic features
  • loss of nerve cells
  • no amyloid plaques
  • tau protein tangles seen in certain FTD, but different from AD tangles
  • loss of nerve cells
  • amyloid plaques
  • tau tangles
Clinical features
  • varying personality and behaviour changes, from apathy to hyperactivity
  • loss of empathy toward others; lack of proper social conduct
  • memory is preserved early on
  • language difficulty
  • compulsive eating and oral fixations
  • repetitive actions
  • begins with memory loss
  • loss of ability to learn new information
  • inability to orient oneself to time and place
  • later, personality and behaviour problems develop
  • possible hallucinations and delusions in later stage




Location

# 8-2-316/5/10, Ground Floor,
Lane Behind Asha Hospital, Road no 14,
Resham Bagh, Banjara Hills,
Hyderabad, Telangana 500034

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